It is widely assumed that selection history accounts of function can support a fully reductive naturalization of functional properties. I argue that this assumption is false. A problem with the alternative causal role account of function in this context is that it invokes the teleological notion of a goal in analysing real function. The selection history account, if it is to have reductive status, must not do the same. But attention to certain cases of selection history in biology, specifically those (...) involving meiotic drive, shows that selection historical explanations are available in the case of items without any plausible function. Making contributions to goals, here fitness, must be introduced as an additional constraint in the analysis, either explicitly, or implicitly by appeal to individual functions or the selection-of/selection-for distinction. (shrink)

1. Marxism and totalitarian democracy, 1818-1850.--v. 2. Classical Marxism, 1850-1895.

In this important collection, the editors argue that medieval philosophy is best studied as an interactive discussion between thinkers working on very much the same problems despite being often widely separated in time or place. Each section opens with at least one selection from a classical philosopher, and there are many points at which the readings chosen refer to other works that the reader will also find in this collection. There is a considerable amount of material from central figures such (...) as Augustine, Abelard, Duns Scotus, and William of Ockham, as well as extensive texts from thinkers in the medieval Islamic world. Each selection is prefaced by a brief introduction by the editors, providing a philosophical and religious background to help make the material more accessible to the reader. This edition, updated throughout, contains a substantial new chapter on medieval psychology and philosophy of mind, with texts from authors not previously represented such as John Buridan and Peter John Olivi. (shrink)

This is a collection of essays touching on four distinct areas of interest to philosophers, lawyers, and political scientists: the philosophical justification for the adversary system; the problems of truth-finding in an adversarial setting; the issue of justice in relation to social policy-making; the right to privacy.

The discovery and engineering of novel fluorescent proteins (FPs) from diverse organisms is yielding fluorophores with exceptional characteristics for live‐cell imaging. In particular, the development of FPs for fluorescence (or Förster) resonance energy transfer (FRET) microscopy is providing important tools for monitoring dynamic protein interactions inside living cells. The increased interest in FRET microscopy has driven the development of many different methods to measure FRET. However, the interpretation of FRET measurements is complicated by several factors including the high fluorescence background, (...) the potential for photoconversion artifacts and the relatively low dynamic range afforded by this technique. Here, we describe the advantages and disadvantages of four methods commonly used in FRET microscopy. We then discuss the selection of FPs for the different FRET methods, identifying the most useful FP candidates for FRET microscopy. The recent success in expanding the FP color palette offers the opportunity to explore new FRET pairs. (shrink)

From the neurophysiological perspective, thinking in dreaming and the quality of dream thought have been considered hallucinatory, bizarre, illogical, improbable, or even impossible. This empirical phenomenological research concentrates on testing whether dream thought can be defined as rational in the sense of an intervening mental process between sensory perception and the creation of meaning, leading to a conclusion or to taking action. From 10 individual dream journals of male participants aged 22–59 years and female participants aged 25–49 years, we delimited (...) four dreams per journal and randomly selected five thought units from each dream for scoring. The units provided a base for testing a hypothesis that the thought processes of dream construction are rational. The results support the hypothesis and demonstrate that eight fundamental rational thought processes can be applied to the dreaming process. (shrink)

This essay contends that Jonathan Bennett gave a passive reading of conatus, and that he misunderstood Spinoza’s conception of mental representation, mistakenly attributing to Spinoza the common, contemporary view that representational content does not supervene on the intrinsic features of representations. A reading of the conatus as an active, motive principle of opposition is presented. It is argued that Spinoza’s notion of representation is best understood as grounded in a conception of causation on which effects bear intrinsic, distinctive structural marks (...) of their causes. (shrink)

This chapter contains sections titled: Introduction Rationalism and the Analytic/Synthetic Distinction A priori Principles I: Davidson on Causation and the Mental Constitutive Principles and Classical Rationalism Classical Rationalism or Kantian Transcendentalism? The Refutation of (Transcendental) Idealism Rationalism Full‐Blown.

Reviews in allegory the approaches taken to the problem of agency by contemporary perspectives in psychology and broader intellectual tradition. The author argues that agency can only be rendered sensible or possible where there is freedom from traditional determinisms and where there is real moral content. It is argued that agency will only be possible when moral relativity is overcome. 2012 APA, all rights reserved).

In this book, Della Rocca traces out the conceptual links between key concepts and principles of Spinoza's system bearing on representation and the mind-body problem. In the course of doing so, he presents and defends a number of new, interesting theses about Spinoza's thought on these matters. The arguments are presented with impressive clarity and in great detail. All in all, the book is a significant contribution to the literature on Spinoza's metaphysics and epistemology, and should be read by anyone (...) with a serious interest in its historical subject or in the two perennial philosophical problems on which it focuses. (shrink)

This paper argues that Donald Davidson’s infamous denial in “A Nice Derangement of Epitaphs” that there is any such thing as a language, though it may not be fully supported by the arguments given for it in that paper, is nonetheless entailed by his semantic views generally, according to which the literal, linguistic meaning of a speaker’s words on an occasion is determined by how the speaker intended to be understood. In favor of this view, and thus against conventional languages, (...) the paper then argues that this understanding of linguistic meaning promises, in a way the conventional view of meaning does not, to make sense of linguistic normativity. (shrink)

The paper argues that Israel Kirzner’s theory of entrepreneurship has been influential on a number of related “dynamic” theories of organization. Kirzner’s theory is animated by a dual concern – the process of rentseeking behavior and the fundamental incompletness of knowledge. Placed in a technological and institutional context, this theory points to the importance of dynamic transaction costs: the coordination costs of acting upon an innovative rent-seeking opportunity. In some contexts, this kind of cost can explain vertical integration; in other (...) contexts, it can explain the reverse phenomenon: vertical disintegration.Cet article soutient que la théorie de l’entrepreneur d’Israel Kirzner a influencé un grand nombre de théories dynamiques de l’organisation. La théorie kirznerienne est animée par un objectif double : – le processus de comportement de recherche de rente et l’incomplétude fondamentale de la connaissance. Replacée dans un contexte technologique et institutionnel, cette théorie souligne l’importance des coûts de transaction dynamiques : les coûts de transaction liés à une opportunité dans la recherche de rente innovante. Dans certaines situations, cette catégorie de coûts peut expliquer l’intégration verticale ; dans d’autres, elle peut expliquer le phénomène inverse : la désintégration verticale. (shrink)

Alfred D. Chandler, Jr. is a worthy successor to Joseph Schumpeter as analyst of the large corporation and its role in economic growth. His new book, Scale and Scope, a comparative history of corporate capitalism in the U. S., Britain, and Germany, is animated by a vision of the large corporation as the leading force in economic growth, outdistancing older owner?managed forms of organization with a superior ability to invest entrepreneurially in large?scale production, mass distribution, and professional management. Chandler's account (...) implicitly relies on a dynamic?capabilities? theory of competition that reveals the fundamental irrelevance of neoclassical theory and policy, including antitrust policy. In some ways, however, Chandler's vision is too narrow, underplaying the role of markets in economic growth. One needs to know how economic systems build capabilities, not merely how the corporate institution does so. Moreover, there is reason to think that the last few decades have seen an organizational revolution with a dynamic rather different from the one that animates Chandler's account. As a result, Chandler's work is important for understanding the present?day issues of industrial competitiveness, but is only one piece of the puzzle. (shrink)

All that we see, all that we touch, all that we perceive, are naught but ideas. There are trees and rivers, to be sure, but these are simply collections of ideas. Is everything, then, in this world an idea or made up of ideas? No. I, for one, am not an idea. Besides ideas there are spirits. I know that I, an active being, exist. It would seem that to know this and to know God exists, nay even for there (...) to be any meaning in what I say when I use the words “I,” “God,” and “spirit,” I would have to have an idea of myself, an idea of God, and an idea of spirit. But this cannot be. Ideas are essentially passive and inert. Spriits are essentially active. How, then, could an idea represent or be an image of a spirit? And what sense is there to something being an idea if it does not represent its object? How, then, can my discourse about spirits have any meaning at all? I have a notion of spirit. (shrink)